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At the immune cell level, melatonin enhances CD4 + /CD8 + T cell proliferation and antigen responsiveness, modulates the Treg/Th1/Th2 balance, promotes macrophage polarization toward the anti-inflammatory M2 phenotype, and augments NK cell cytotoxicity

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Int J Mol Sci, 18 (3), doi: Chung, K

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